Ovulation induction in polycystic ovary syndrome.

P-62: Extended Letrozole Therapy for Ovulation Induction in Women with Polycystic Ovary Syndrome

Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in young women which has different clinical consequences. This study was conducted to evaluate the outcome of long or extended letrozole therapy for induction of ovulation in patients with polycystic ovary syndrome (PCOS). Materials and Methods: This prospective controlled study was conducted in a university hospital on...

Surgical Ovulation Induction in Women with Polycystic Ovary Syndrome: A Systematic Review

Background: Currently clomiphene citrate is the first-line treatment to induce ovulation in women with polycystic ovarian syndrome (PCOS). Surgical therapy with laparoscopic ovarian drilling (LOD) may avoid or reduce the need for gonadotropins. Objective: To determine the effectiveness and safety of LOD compared with ovulation induction in subfertile women with clomiphene-resistant PCOS. Search...

The Effect of Flutamide on Ovulation Induction in PCOS Patients

Comparison between Unilateral and Bilateral Ovarian Drilling in Clomiphene Citrate Resistance Polycystic Ovary Syndrome Patients: A Randomized Clinical Trial of Efficacy

Background Laparoscopic ovarian drilling (LOD) is an alternative method to induce ovulation in polycystic ovary syndrome (PCOS) patients with clomiphene citrate (CC) resistant instead of gonadotropins. This study aimed to compare the efficacy of unilateral LOD (ULOD) versus bilateral LOD (BLOD) in CC resistance PCOS patients in terms of ovulation and pregnancy rates. MaterialsAndMethods In a pr...

O-29: Pregnancies Following the Use of SequentialTreatment of Metformin and IncrementalDoses of Letrozole in Clomiphen-ResistantWomen with Polycystic Ovary Syndrome

Background: Clomiphen citrate (CC) is the first line therapy for women with infertility and poly cystic ovary syndrome( PCOS).However, 20-25% of women are resistant to CC and do not ovulate. The Background of this study is to evaluate the efficacy of sequential treatment of metformin and incremental doses of letrozole in induction of ovulation in cases of clomiphen citrateresistant (CC- R) PCOS...

I-22: Decision Trees for Identifying Predictor of Treatment Effectiveness in Clinical Trials and Its Application to Ovulation in a Study of Women with Polycystic Ovary Syndrome

Background: Double-blind, randomized clinical trials are the preferred approach to demonstrate the effectiveness of one treatment against another. The comparison is, however, made on the average group effects. While patients and clinicians have always struggled to understand why patients respond differently to the same treatment, and while much hope has been held out for the nascent field of pr...